Heynen, Guus J. J. E.: search on Z-Library

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1

From Pyrazolones to Azaindoles: Evolution of Active-Site SHP2 Inhibitors Based on Scaffold Hopping and Bioisosteric Replacement

Mostinski, Yelena, Heynen, Guus J. J. E., LÃ³pez-Alberca, Maria Pascual, Paul, Jerome, Miksche, Sandra, Radetzki, Silke, Schaller, David, Shanina, Elena, Seyffarth, Carola, Kolomeets, Yuliya, Ziebart,

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 4.81 MB

2020

2

Cancer Stem Cells Regulate Cancer-Associated Fibroblasts via Activation of Hedgehog Signaling in Mammary Gland Tumors

Valenti, Giovanni, Quinn, Hazel M., Heynen, Guus J.J.E., Lan, Linxiang, Holland, Jane D., Vogel, Regina, Wulf-Goldenberg, Annika, Birchmeier, Walter

Journal:

Cancer Research

Year:

2017

Language:

english

File:

PDF, 10.62 MB

english, 2017

3

Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase

Ruess, Dietrich A., Heynen, Guus J., Ciecielski, Katrin J., Ai, Jiaoyu, Berninger, Alexandra, Kabacaoglu, Derya, Görgülü, Kivanc, Dantes, Zahra, Wörmann, Sonja M., Diakopoulos, Kalliope N., Karpathaki

Journal:

Nature Medicine

Year:

2018

Language:

english

File:

PDF, 2.56 MB

english, 2018

4

PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs

Prahallad, Anirudh, Heynen, Guus J.J.E., Germano, Giovanni, Willems, Stefan M., Evers, Bastiaan, Vecchione, Loredana, Gambino, Valentina, Lieftink, Cor, Beijersbergen, Roderick L., Di Nicolantonio, Fe

Journal:

Year:

2015

Language:

english

File:

PDF, 2.44 MB

english, 2015

5

Resistance to targeted cancer drugs through hepatocyte growth factor signaling

Heynen, Guus JJE, Fonfara, Aldona, Bernards, René

Journal:

Year:

2014

Language:

english

File:

PDF, 1.22 MB

english, 2014

6

Decreased glutathione biosynthesis contributes to EGFR T790M-driven erlotinib resistance in non-small cell lung cancer

Li, Hongde, Stokes, William, Chater, Emily, Roy, Rajat, de Bruin, Elza, Hu, Yili, Liu, Zhigang, Smit, Egbert F, Heynen, Guus JJE, Downward, Julian, Seckl, Michael J, Wang, Yulan, Tang, Huiru, Pardo, O

Journal:

Year:

2016

Language:

english

File:

PDF, 2.62 MB

english, 2016

7

Results from the Use of a Preshaped Lead for Single-Pass VDD/DDD Stimulation

CARSTEN WALTER ISRAEL, IB MUNKSGAARD KRUSE, ROBERT VAN MECHELEN, GUUS KROES, HENRY HEYNEN, NICO LOKHOFF

Journal:

Pacing and Clinical Electrophysiology

Year:

1999

Language:

english

File:

PDF, 3.17 MB

english, 1999

8

Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase

Ruess, Dietrich, Heynen, Guus, Ciecielski, Katrin, Birchmeier, Walter, Schmid, Roland, Algül, Hana

Journal:

Year:

2018

Language:

english

File:

PDF, 48 KB

english, 2018

9

Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma

Sun, Chong, Wang, Liqin, Huang, Sidong, Heynen, Guus J. J. E., Prahallad, Anirudh, Robert, Caroline, Haanen, John, Blank, Christian, Wesseling, Jelle, Willems, Stefan M., Zecchin, Davide, Hobor, Sebas

Journal:

Year:

2014

Language:

english

File:

PDF, 6.03 MB

english, 2014

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